Major Depressive Disorder (MDD)
![](http://tmscenterofsouthernillinois.com/wp-content/uploads/2017/10/depressed-person.jpg)
Treatment is often challenging: anĀ estimated 20% -40% of patients do not benefits sufficiently from existing antidepressant interventionĀ including trials of medication and psychotherapy (Greden 2001)
16.1 million US adults with MDD
7.2 million treated
4.5 million poorly served